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Queensland researcher David Harrich develops gene therapy which could stop HIV from turning deadly

Queensland Institute of Medical Research scientist David Harrich will begin animal trials this year, with experiments in humans are still five years away. Associate Professor Harrich has manipulated an HIV protein involved in gene expression, known as Tat, and turned it into a weapon against the virus.

Published
16 January 2013
From
news.com.au
CMV infection may contribute to the size of the latent HIV reservoir

The presence of cytomegalovirus (CMV) in blood and semen is associated with higher levels of HIV DNA in blood, investigators from the United States report in the

Published
16 January 2013
By
Michael Carter
Scientists discover how HIV virus gains access to carrier immune cells to spread infection

Scientists have identified how HIV, the virus that causes AIDS, enters the cells of the immune system enabling it to be dispersed throughout an organism.

Published
19 December 2012
From
Science Daily
Cancer drug shows promise in eradicating latent HIV infection

Breakthrough drugs help people to live longer with HIV, but more research is needed for an actual cure. One challenge involves eradicating the virus when it is latent in the body. Research in the December 2012 issue of the Journal of Leukocyte Biology suggests the cancer drug, JQ1, may be useful in purging latent HIV infection by activating the virus in the presence of potent therapy -- essentially a dead end for the virus.

Published
29 November 2012
From
Eurekalert Medicine & Health
How AIDS ends: 15 visionaries write the final chapter on HIV/AIDS

When the history of HIV/AIDS is at last written, what will the final chapter look like? With contributions from: Timothy Ray Brown, Jeanne White Ginder, Cleve Jones, Barbara Lee, Mark Dybul, Paul Farmer, Robert Gallo, Mervyn Silverman, Diane Havlir, Scott Wiener, LZ Granderson, Hank Plante, Eduardo Xol, and Neil Giuliano.

Published
28 November 2012
From
San Francisco AIDS Foundation
Survival gene may be key to controlling HIV and hepatitis

A newly discovered gene that is essential for embryo survival could also hold the key to treating and potentially controlling chronic infections such as HIV, hepatitis and tuberculosis. The gene, called Arih2, is fundamental to the function of the immune system - making critical decisions about whether to switch on the immune response to an infection.

Published
27 November 2012
From
Science Daily
Pegylated interferon may maintain HIV suppression and reduce viral DNA integration

Adding pegylated interferon alfa to antiretroviral therapy (ART) for HIV may help some people control viral replication when they interrupt treatment, according to a small study reported at this year's Conference on Retroviruses and Opportunistic Infections (CROI 2012) and published in the October 26, 2012, advance online edition of the Journal of Infectious Diseases.

Published
12 November 2012
From
HIVandHepatitis.com
Brief Treatment Interruptions for Cure Studies Are Safe, Well-Tolerated

Short treatment interruptions of HIV antiretroviral regimens are both safe and well-tolerated, which is good news for scientists pursuing functional cures. 

Published
05 November 2012
From
AIDSMeds
Groundbreaking Research Discovers Possible New Way To Fight HIV

New research has disocvered how the HIV virus targets memory T-cells or "veterans" instead of naive "virgin" T-cells. This could potentially change how drugs are used to halt the virus. This research finds that HIV exploits the fact that memory T-cells are more mobile; it uses the cytoskeleton, the internal structure of the cell, as a "conveyor belt" to carry it deep within the cell and to the nucleus. The researchers are now looking at whether drugs that reduce cancer cell motility could reduce the "attractiveness" of T-memory cells to HIV.

Published
25 October 2012
From
Medical News Today
AIDS Progression May Be Affected By Diverse Intestinal Viruses

In monkeys and humans with AIDS, damage to the gastrointestinal tract is common, contributing to activation of the immune system, progressive immune deficiency, and ultimately advanced AIDS.

Published
15 October 2012
From
HIV / AIDS News From Medical News Today

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